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Targeting c-Met Receptor Overcomes TRAIL-Resistance in Brain Tumors

Tumor necrosis factor related apoptosis-inducing ligand (TRAIL) induced apoptosis specifically in tumor cells. However, with approximately half of all known tumor lines being resistant to TRAIL, the identification of TRAIL sensitizers and their mechanism of action become critical to broadly use TRAI...

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Detalles Bibliográficos
Autores principales: Du, Wanlu, Uslar, Liubov, Sevala, Sindhura, Shah, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991662/
https://www.ncbi.nlm.nih.gov/pubmed/24748276
http://dx.doi.org/10.1371/journal.pone.0095490