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Nanoparticle Incorporation of Melittin Reduces Sperm and Vaginal Epithelium Cytotoxicity
Melittin is a cytolytic peptide component of bee venom which rapidly integrates into lipid bilayers and forms pores resulting in osmotic lysis. While the therapeutic utility of free melittin is limited by its cytotoxicity, incorporation of melittin into the lipid shell of a perfluorocarbon nanoparti...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991669/ https://www.ncbi.nlm.nih.gov/pubmed/24748389 http://dx.doi.org/10.1371/journal.pone.0095411 |