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Nanoparticle Incorporation of Melittin Reduces Sperm and Vaginal Epithelium Cytotoxicity

Melittin is a cytolytic peptide component of bee venom which rapidly integrates into lipid bilayers and forms pores resulting in osmotic lysis. While the therapeutic utility of free melittin is limited by its cytotoxicity, incorporation of melittin into the lipid shell of a perfluorocarbon nanoparti...

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Detalles Bibliográficos
Autores principales: Jallouk, Andrew P., Moley, Kelle H., Omurtag, Kenan, Hu, Grace, Lanza, Gregory M., Wickline, Samuel A., Hood, Joshua L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991669/
https://www.ncbi.nlm.nih.gov/pubmed/24748389
http://dx.doi.org/10.1371/journal.pone.0095411