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Histone Acetylation and CREB Binding Protein Are Required for Neuronal Resistance against Ischemic Injury

Epigenetic transcriptional regulation by histone acetylation depends on the balance between histone acetyltransferase (HAT) and deacetylase activities (HDAC). Inhibition of HDAC activity provides neuroprotection, indicating that the outcome of cerebral ischemia depends crucially on the acetylation s...

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Detalles Bibliográficos
Autores principales: Yildirim, Ferah, Ji, Shengbo, Kronenberg, Golo, Barco, Angel, Olivares, Roman, Benito, Eva, Dirnagl, Ulrich, Gertz, Karen, Endres, Matthias, Harms, Christoph, Meisel, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991684/
https://www.ncbi.nlm.nih.gov/pubmed/24748101
http://dx.doi.org/10.1371/journal.pone.0095465