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Histone Acetylation and CREB Binding Protein Are Required for Neuronal Resistance against Ischemic Injury
Epigenetic transcriptional regulation by histone acetylation depends on the balance between histone acetyltransferase (HAT) and deacetylase activities (HDAC). Inhibition of HDAC activity provides neuroprotection, indicating that the outcome of cerebral ischemia depends crucially on the acetylation s...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991684/ https://www.ncbi.nlm.nih.gov/pubmed/24748101 http://dx.doi.org/10.1371/journal.pone.0095465 |