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Pathway-Specific Engineered Mouse Allograft Models Functionally Recapitulate Human Serous Epithelial Ovarian Cancer

The high mortality rate from ovarian cancers can be attributed to late-stage diagnosis and lack of effective treatment. Despite enormous effort to develop better targeted therapies, platinum-based chemotherapy still remains the standard of care for ovarian cancer patients, and resistance occurs at a...

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Detalles Bibliográficos
Autores principales: Szabova, Ludmila, Bupp, Sujata, Kamal, Muhaymin, Householder, Deborah B., Hernandez, Lidia, Schlomer, Jerome J., Baran, Maureen L., Yi, Ming, Stephens, Robert M., Annunziata, Christina M., Martin, Philip L., Van Dyke, Terry A., Ohler, Zoe Weaver, Difilippantonio, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991711/
https://www.ncbi.nlm.nih.gov/pubmed/24748377
http://dx.doi.org/10.1371/journal.pone.0095649