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Physiologically Realistic and Validated Mathematical Liver Model Revels Hepatobiliary Transfer Rates for Gd-EOB-DTPA Using Human DCE-MRI Data

OBJECTIVES: Diffuse liver disease (DLD), such as non-alcoholic fatty liver disease (NASH) and cirrhosis, is a rapidly growing problem throughout the Westernized world. Magnetic resonance imaging (MRI), based on uptake of the hepatocyte-specific contrast agent (CA) Gd-EOB-DTPA, is a promising non-inv...

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Detalles Bibliográficos
Autores principales: Forsgren, Mikael Fredrik, Leinhard, Olof Dahlqvist, Dahlström, Nils, Cedersund, Gunnar, Lundberg, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991717/
https://www.ncbi.nlm.nih.gov/pubmed/24748411
http://dx.doi.org/10.1371/journal.pone.0095700