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Local translation of TC10 is required for membrane expansion during axon outgrowth

The surface of developing axons expands in a process mediated by the exocyst complex. The spatial-temporal regulation of the exocyst is only partially understood. Here we report that stimulated membrane enlargement in dorsal root ganglion (DRG) axons is triggered by intra-axonal synthesis of TC10, a...

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Detalles Bibliográficos
Autores principales: Gracias, Neilia G., Shirkey-Son, Nicole J., Hengst, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991842/
https://www.ncbi.nlm.nih.gov/pubmed/24667291
http://dx.doi.org/10.1038/ncomms4506