Identification of Transcriptional and Metabolic Programs Related to Mammalian Cell Size

BACKGROUND: Regulation of cell size requires coordination of growth and proliferation. Conditional loss of cyclin-dependent kinase 1 in mice permits hepatocyte growth without cell division, allowing us to study cell size in vivo using transcriptomics and metabolomics. RESULTS: Larger cells displayed...

Descripción completa

Detalles Bibliográficos
Autores principales: Miettinen, Teemu P., Pessa, Heli K.J., Caldez, Matias J., Fuhrer, Tobias, Diril, M. Kasim, Sauer, Uwe, Kaldis, Philipp, Björklund, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991852/
https://www.ncbi.nlm.nih.gov/pubmed/24613310
http://dx.doi.org/10.1016/j.cub.2014.01.071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991852/
https://www.ncbi.nlm.nih.gov/pubmed/24613310
http://dx.doi.org/10.1016/j.cub.2014.01.071

Ejemplares similares