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Cyclooxygenase metabolism mediates vasorelaxation to 2-arachidonoylglycerol (2-AG) in human mesenteric arteries

OBJECTIVE: The vasorelaxant effect of 2-arachidonoylglycerol (2-AG) has been well characterised in animals. 2-AG is present in human vascular cells and is up-regulated in cardiovascular pathophysiology. However, the acute vascular actions of 2-AG have not been explored in humans. APPROACH: Mesenteri...

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Detalles Bibliográficos
Autores principales: Stanley, Christopher P., O'Sullivan, Saoirse E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992009/
https://www.ncbi.nlm.nih.gov/pubmed/24548820
http://dx.doi.org/10.1016/j.phrs.2014.02.001