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A magic bullet to specifically eliminate mutated mitochondrial genomes from patients' cells
When mitochondrial diseases result from mutations found in the mitochondrial DNA, engineered mitochondrial-targeted nucleases such as mitochondrial-targeted zinc finger nucleases are shown to specifically eliminate the mutated molecules, leaving the wild-type mitochondrial DNA intact to replicate an...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992069/ https://www.ncbi.nlm.nih.gov/pubmed/24623377 http://dx.doi.org/10.1002/emmm.201303769 |