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Activation of the PI3K/AKT pathway correlates with prognosis in stage II colon cancer

BACKGROUND: Patients with UICC/AJCC stage II colon cancer have a high 5-year overall survival rate after surgery. Nevertheless, a significant subgroup of patients develops tumour recurrence. Currently, there are no clinically established biomarkers available to identify this patient group. We applie...

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Detalles Bibliográficos
Autores principales: Malinowsky, K, Nitsche, U, Janssen, K-P, Bader, F G, Späth, C, Drecoll, E, Keller, G, Höfler, H, Slotta-Huspenina, J, Becker, K-F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992486/
https://www.ncbi.nlm.nih.gov/pubmed/24619078
http://dx.doi.org/10.1038/bjc.2014.100