Adaptive designs for clinical trials assessing biomarker-guided treatment strategies

BACKGROUND: The Biomarker Strategy Design has been proposed for trials assessing the value of a biomarker in guiding treatment in oncology. In such trials, patients are randomised to either receive the standard chemotherapy treatment or a biomarker-directed treatment arm, in which biomarker status i...

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Detalles Bibliográficos
Autores principales: Wason, J, Marshall, A, Dunn, J, Stein, R C, Stallard, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992506/
https://www.ncbi.nlm.nih.gov/pubmed/24667651
http://dx.doi.org/10.1038/bjc.2014.156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992506/
https://www.ncbi.nlm.nih.gov/pubmed/24667651
http://dx.doi.org/10.1038/bjc.2014.156

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