Biliverdin's regulation of reactive oxygen species signalling leads to potent inhibition of proliferative and angiogenic pathways in head and neck cancer

BACKGROUND: In this study, we evaluate whether the use of biliverdin (BV), a natural non-toxic antioxidant product of haeme catabolism, can suppress head and neck squamous cell carcinoma (HNSCC) cell proliferation and improve the tumour survival both in vitro and in vivo. Furthermore, we investigate...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, J, Nagda, D A, Lajud, S A, Kumar, S, Mouchli, A, Bezpalko, O, O'Malley, B W, Li, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992514/
https://www.ncbi.nlm.nih.gov/pubmed/24569474
http://dx.doi.org/10.1038/bjc.2014.98

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992514/
https://www.ncbi.nlm.nih.gov/pubmed/24569474
http://dx.doi.org/10.1038/bjc.2014.98

Ejemplares similares