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Biliverdin's regulation of reactive oxygen species signalling leads to potent inhibition of proliferative and angiogenic pathways in head and neck cancer
BACKGROUND: In this study, we evaluate whether the use of biliverdin (BV), a natural non-toxic antioxidant product of haeme catabolism, can suppress head and neck squamous cell carcinoma (HNSCC) cell proliferation and improve the tumour survival both in vitro and in vivo. Furthermore, we investigate...
Autores principales: | Zheng, J, Nagda, D A, Lajud, S A, Kumar, S, Mouchli, A, Bezpalko, O, O'Malley, B W, Li, D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992514/ https://www.ncbi.nlm.nih.gov/pubmed/24569474 http://dx.doi.org/10.1038/bjc.2014.98 |
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