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Expansion of Foxp3(+) T-cell populations by Candida albicans enhances both Th17-cell responses and fungal dissemination after intravenous challenge

Candida albicans remains the fungus most frequently associated with nosocomial bloodstream infection. In disseminated candidiasis, the role of Foxp3(+) regulatory T (Treg) cells remains largely unexplored. Our aims were to characterize Foxp3(+) Treg-cell activation in a murine intravenous challenge...

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Detalles Bibliográficos
Autores principales: Whibley, Natasha, MacCallum, Donna M, Vickers, Mark A, Zafreen, Sadia, Waldmann, Herman, Hori, Shohei, Gaffen, Sarah L, Gow, Neil A R, Barker, Robert N, Hall, Andrew M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley-VCH Verlag GmbH & Co. KGaA 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992851/
https://www.ncbi.nlm.nih.gov/pubmed/24435677
http://dx.doi.org/10.1002/eji.201343604