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c-Jun N-terminal kinase regulates mGluR-dependent expression of post-synaptic FMRP target proteins

Fragile X syndrome (FXS) is caused by the loss of functional fragile X mental retardation protein (FMRP). Loss of FMRP results in an elevated basal protein expression profile of FMRP targeted mRNAs, a loss of local metabotropic glutamate receptor (mGluR)-regulated protein synthesis, exaggerated long...

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Detalles Bibliográficos
Autores principales: Schmit, Travis L, Dowell, James A, Maes, Margaret E, Wilhelm, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992883/
https://www.ncbi.nlm.nih.gov/pubmed/24047560
http://dx.doi.org/10.1111/jnc.12453