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Perturbations to the IGF1 growth pathway and adult energy homeostasis following disruption of mouse chromosome 12 imprinting

AIM: Disruption to insulin-like growth factor (IGF) signalling pathways during early life causes growth retardation and defects of developing metabolic organs that can alter set points of energy homeostasis for a lifetime. Inheritance of two maternal copies of human chromosome 14q32.2 (Temple syndro...

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Detalles Bibliográficos
Autores principales: Charalambous, M, da Rocha, S T, Hernandez, A, Ferguson-Smith, A C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992899/
https://www.ncbi.nlm.nih.gov/pubmed/24034272
http://dx.doi.org/10.1111/apha.12160