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Heme oxygenase-1 induction alters chemokine regulation and ameliorates human immunodeficiency virus-type-1 infection in lipopolysaccharide-stimulated macrophages

We have elucidated a putative mechanism for the host resistance against HIV-1 infection of primary human monocyte-derived macrophages (MDM) stimulated with lipopolysaccharide (LPS). We show that LPS-activated MDM both inhibited HIV-1 entry into the cells and were refractory to post-entry productive...

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Detalles Bibliográficos
Autores principales: Zhou, Zhao-Hua, Kumari, Namita, Nekhai, Sergei, Clouse, Kathleen A., Wahl, Larry M., Yamada, Kenneth M., Dhawan, Subhash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992914/
https://www.ncbi.nlm.nih.gov/pubmed/23665328
http://dx.doi.org/10.1016/j.bbrc.2013.04.095