Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-κB-mediated inflammatory response

The generation of reactive oxygen species plays a pivotal role in both acute and chronic glomerular injuries in patients with lupus nephritis. Since the transcription factor Nrf2 is a major regulator of the antioxidant response and is a primary cellular defense mechanism we sought to determine a rol...

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Detalles Bibliográficos
Autores principales: Jiang, Tao, Tian, Fei, Zheng, Hongting, Whitman, Samantha A., Lin, Yifeng, Zhang, Zhigang, Zhang, Nong, Zhang, Donna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992978/
https://www.ncbi.nlm.nih.gov/pubmed/24025640
http://dx.doi.org/10.1038/ki.2013.343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992978/
https://www.ncbi.nlm.nih.gov/pubmed/24025640
http://dx.doi.org/10.1038/ki.2013.343

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