Integrin Modulating Therapies Prevent Fibrosis and Autoimmunity in Genetic Mouse Models of Scleroderma

In systemic sclerosis (SSc), a common and etiologically mysterious form of scleroderma (defined as pathologic fibrosis of the skin), previously healthy adults acquire fibrosis of the skin and viscera in association with autoantibodies [1]. Familial recurrence is extremely rare and causal genes have...

Descripción completa

Detalles Bibliográficos
Autores principales: Gerber, Elizabeth E., Gallo, Elena M., Fontana, Stefani C., Davis, Elaine C., Wigley, Fredrick M., Huso, David L., Dietz, Harry C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992987/
https://www.ncbi.nlm.nih.gov/pubmed/24107997
http://dx.doi.org/10.1038/nature12614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992987/
https://www.ncbi.nlm.nih.gov/pubmed/24107997
http://dx.doi.org/10.1038/nature12614

Ejemplares similares