Trained Immunity or Tolerance: Opposing Functional Programs Induced in Human Monocytes after Engagement of Various Pattern Recognition Receptors

Upon priming with Candida albicans or with the fungal cell wall component β-glucan, monocytes respond with an increased cytokine production upon restimulation, a phenomenon termed “trained immunity.” In contrast, the prestimulation of monocytes with lipopolysaccharide has long been known to induce t...

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Detalles Bibliográficos
Autores principales: Ifrim, Daniela C., Quintin, Jessica, Joosten, Leo A. B., Jacobs, Cor, Jansen, Trees, Jacobs, Liesbeth, Gow, Neil A. R., Williams, David L., van der Meer, Jos W. M., Netea, Mihai G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Clinical Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993125/
https://www.ncbi.nlm.nih.gov/pubmed/24521784
http://dx.doi.org/10.1128/CVI.00688-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993125/
https://www.ncbi.nlm.nih.gov/pubmed/24521784
http://dx.doi.org/10.1128/CVI.00688-13

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