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An Unbiased Genetic Screen Reveals the Polygenic Nature of the Influenza Virus Anti-Interferon Response

Influenza A viruses counteract the cellular innate immune response at several steps, including blocking RIG I-dependent activation of interferon (IFN) transcription, interferon (IFN)-dependent upregulation of IFN-stimulated genes (ISGs), and the activity of various ISG products; the multifunctional...

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Detalles Bibliográficos
Autores principales: Pérez-Cidoncha, Maite, Killip, Marian J., Oliveros, Juan C., Asensio, Víctor J., Fernández, Yolanda, Bengoechea, José A., Randall, Richard E., Ortín, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993829/
https://www.ncbi.nlm.nih.gov/pubmed/24574395
http://dx.doi.org/10.1128/JVI.00014-14