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A New Group of Phage Anti-CRISPR Genes Inhibits the Type I-E CRISPR-Cas System of Pseudomonas aeruginosa

CRISPR-Cas systems are one of the most widespread phage resistance mechanisms in prokaryotes. Our lab recently identified the first examples of phage-borne anti-CRISPR genes that encode protein inhibitors of the type I-F CRISPR-Cas system of Pseudomonas aeruginosa. A key question arising from this w...

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Detalles Bibliográficos
Autores principales: Pawluk, April, Bondy-Denomy, Joseph, Cheung, Vivian H. W., Maxwell, Karen L., Davidson, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993853/
https://www.ncbi.nlm.nih.gov/pubmed/24736222
http://dx.doi.org/10.1128/mBio.00896-14