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Models Derived from In Vitro Analyses of Spleen, Liver, and Lung Leukocyte Functions Predict Vaccine Efficacy against the Francisella tularensis Live Vaccine Strain (LVS)

Currently, there are no licensed vaccines and no correlates of protection against Francisella tularensis, which causes tularemia. We recently demonstrated that measuring in vitro control of intramacrophage bacterial growth by murine F. tularensis-immune splenocytes, as well as transcriptional analys...

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Detalles Bibliográficos
Autores principales: De Pascalis, Roberto, Chou, Alicia Y., Ryden, Patrik, Kennett, Nikki J., Sjöstedt, Anders, Elkins, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993856/
https://www.ncbi.nlm.nih.gov/pubmed/24713322
http://dx.doi.org/10.1128/mBio.00936-13