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Direct Access to Functionalized Azepanes by Cross-Coupling with α-Halo Eneformamides
[Image: see text] The synthesis of functionalized azepanes was accomplished through the palladium-mediated cross-coupling of α-halo eneformamides with mostly unactivated nucleophiles under mild conditions. Alkenylations proceeded with excellent stereoselectivitiy. In most cases, high yields of the c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993866/ https://www.ncbi.nlm.nih.gov/pubmed/24456197 http://dx.doi.org/10.1021/ol403671s |