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Enhanced Cellular Entry and Efficacy of Tat Conjugates by Rational Design of the Auxiliary Segment
[Image: see text] Conjugation with a cell penetrating peptide such as Tat presents an effective approach to improve the intracellular accumulation of molecules with low membrane permeability. This strategy, however, leads to a reduced cellular entry of molecules that can cross cell membrane effectiv...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993903/ https://www.ncbi.nlm.nih.gov/pubmed/24437690 http://dx.doi.org/10.1021/mp400619v |