Enhanced Cellular Entry and Efficacy of Tat Conjugates by Rational Design of the Auxiliary Segment

[Image: see text] Conjugation with a cell penetrating peptide such as Tat presents an effective approach to improve the intracellular accumulation of molecules with low membrane permeability. This strategy, however, leads to a reduced cellular entry of molecules that can cross cell membrane effectiv...

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Detalles Bibliográficos
Autores principales: Zhang, Pengcheng, Lock, Lye Lin, Cheetham, Andrew G., Cui, Honggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993903/
https://www.ncbi.nlm.nih.gov/pubmed/24437690
http://dx.doi.org/10.1021/mp400619v

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