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A Myristoylated Cell-Penetrating Peptide Bearing a Transferrin Receptor-Targeting Sequence for Neuro-Targeted siRNA Delivery

[Image: see text] Many neurodegenerative disorders (NDDs) are characterized by aggregation of aberrant proteins and extensive oxidative stress in brain cells. As a treatment option for NDDs, RNA interference (RNAi) is a promising approach to suppress the activation of abnormal genes and negative reg...

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Detalles Bibliográficos
Autores principales: Youn, Pilju, Chen, Yizhe, Furgeson, Darin Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993914/
https://www.ncbi.nlm.nih.gov/pubmed/24387132
http://dx.doi.org/10.1021/mp400446v