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pH-Dependent Coordination of Pb(2+) to Metallothionein2: Structures and Insight into Lead Detoxification

[Image: see text] Lead is a toxic heavy metal whose detoxification in organisms is mainly carried out by its coordination with some metalloproteins such as metallothioneins (MTs). Two Pb–MT complexes, named as Pb(7)–MT2(I) and Pb(7)–MT2(II), form under neutral and weakly acidic conditions, respectiv...

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Detalles Bibliográficos
Autores principales: He, Yonghui, Liu, Mengmeng, Darabedian, Narek, Liang, Yizeng, Wu, Deyin, Xiang, Juan, Zhou, Feimeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993925/
https://www.ncbi.nlm.nih.gov/pubmed/24559479
http://dx.doi.org/10.1021/ic402452s