Influence of Oligospermines Architecture on Their Suitability for siRNA Delivery

[Image: see text] Spermines are naturally abundant polyamines that partially condense nucleic acids and exhibit the proton-sponge effect in an acidic environment. However, spermines show a limited efficiency for transfecting nucleic acids because of their low molecular weight. Therefore, spermines n...

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Detalles Bibliográficos
Autores principales: Elsayed, Maha, Corrand, Vincent, Kolhatkar, Vidula, Xie, Yuran, Kim, Na Hyung, Kolhatkar, Rohit, Merkel, Olivia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993926/
https://www.ncbi.nlm.nih.gov/pubmed/24552396
http://dx.doi.org/10.1021/bm401849d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993926/
https://www.ncbi.nlm.nih.gov/pubmed/24552396
http://dx.doi.org/10.1021/bm401849d

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