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Newborn Mouse Lens Proteome and Its Alteration by Lysine 6 Mutant Ubiquitin

[Image: see text] Ubiquitin is a tag that often initiates degradation of proteins by the proteasome in the ubiquitin proteasome system. Targeted expression of K6W mutant ubiquitin (K6W-Ub) in the lens results in defects in lens development and cataract formation, suggesting critical functions for ub...

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Detalles Bibliográficos
Autores principales: Shang, Fu, Wilmarth, Phillip A., Chang, Min-lee, Liu, Ke, David, Larry L., Caceres, Maria Andrea, Wawrousek, Eric, Taylor, Allen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993935/
https://www.ncbi.nlm.nih.gov/pubmed/24450463
http://dx.doi.org/10.1021/pr400801v