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A Chemical and Kinetic Perspective on Base Excision Repair of DNA

[Image: see text] Our cellular genome is continuously exposed to a wide spectrum of exogenous and endogenous DNA damaging agents. These agents can lead to formation of an extensive array of DNA lesions including single- and double-stranded breaks, inter- and intrastrand cross-links, abasic sites, an...

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Detalles Bibliográficos
Autores principales: Schermerhorn, Kelly M., Delaney, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993943/
https://www.ncbi.nlm.nih.gov/pubmed/24646203
http://dx.doi.org/10.1021/ar400275a