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Regulator of G-Protein Signaling 19 (RGS19) and Its Partner Gα-Inhibiting Activity Polypeptide 3 (GNAI3) Are Required for zVAD-Induced Autophagy and Cell Death in L929 Cells

Autophagy has diverse biological functions and is involved in many biological processes. The L929 cell death induced by the pan-caspase inhibitor benzyloxycarbonyl-Val-Ala-Asp-(OMe)-fluoromethyl ketone (zVAD) was shown to be an autophagy-mediated death for which RIP1 and RIP3 were both required. It...

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Detalles Bibliográficos
Autores principales: Wu, Ting, Li, Yuanyue, Huang, Deli, Han, Felicia, Zhang, Ying-Ying, Zhang, Duan-Wu, Han, Jiahuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994006/
https://www.ncbi.nlm.nih.gov/pubmed/24751948
http://dx.doi.org/10.1371/journal.pone.0094634