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PEG-IFN Alpha but Not Ribavirin Alters NK Cell Phenotype and Function in Patients with Chronic Hepatitis C

BACKGROUND: Ribavirin (RBV) remains part of several interferon-free treatment strategies even though its mechanisms of action are still not fully understood. One hypothesis is that RBV increases responsiveness to type I interferons. Pegylated Interferon alpha (PEG-IFNa) has recently been shown to al...

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Detalles Bibliográficos
Autores principales: Markova, Antoaneta A., Mihm, Ulrike, Schlaphoff, Verena, Lunemann, Sebastian, Filmann, Natalie, Bremer, Birgit, Berg, Thomas, Sarrazin, Christoph, Zeuzem, Stefan, Manns, Michael P., Cornberg, Markus, Herrmann, Eva, Wedemeyer, Heiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994015/
https://www.ncbi.nlm.nih.gov/pubmed/24751903
http://dx.doi.org/10.1371/journal.pone.0094512