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Palmitoylation of the Immunity Related GTPase, Irgm1: Impact on Membrane Localization and Ability to Promote Mitochondrial Fission

The Immunity-Related GTPases (IRG) are a family of large GTPases that mediate innate immune responses. Irgm1 is particularly critical for immunity to bacteria and protozoa, and for inflammatory homeostasis in the intestine. Although precise functions for Irgm1 have not been identified, prior studies...

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Detalles Bibliográficos
Autores principales: Henry, Stanley C., Schmidt, Elyse A., Fessler, Michael B., Taylor, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994021/
https://www.ncbi.nlm.nih.gov/pubmed/24751652
http://dx.doi.org/10.1371/journal.pone.0095021