Loss of PINK1 Impairs Stress-Induced Autophagy and Cell Survival

The mitochondrial kinase PINK1 and the ubiquitin ligase Parkin are participating in quality control after CCCP- or ROS-induced mitochondrial damage, and their dysfunction is associated with the development and progression of Parkinson's disease. Furthermore, PINK1 expression is also induced by...

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Detalles Bibliográficos
Autores principales: Parganlija, Dajana, Klinkenberg, Michael, Domínguez-Bautista, Jorge, Hetzel, Miriam, Gispert, Suzana, Chimi, Marthe A., Dröse, Stefan, Mai, Sören, Brandt, Ulrich, Auburger, Georg, Jendrach, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994056/
https://www.ncbi.nlm.nih.gov/pubmed/24751806
http://dx.doi.org/10.1371/journal.pone.0095288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994056/
https://www.ncbi.nlm.nih.gov/pubmed/24751806
http://dx.doi.org/10.1371/journal.pone.0095288

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