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Inhibition of Paracoccidioides lutzii Pb01 Isocitrate Lyase by the Natural Compound Argentilactone and Its Semi-Synthetic Derivatives

The dimorphic fungus Paracoccidioides spp. is responsible for paracoccidioidomycosis, the most prevalent systemic mycosis in Latin America, causing serious public health problems. Adequate treatment of mycotic infections is difficult, since fungi are eukaryotic organisms with a structure and metabol...

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Detalles Bibliográficos
Autores principales: do Prado, Renata Silva, Alves, Ricardo Justino, de Oliveira, Cecília Maria Alves, Kato, Lucília, da Silva, Roosevelt Alves, Quintino, Guilherme Oliveira, do Desterro Cunha, Silvio, de Almeida Soares, Célia Maria, Pereira, Maristela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994062/
https://www.ncbi.nlm.nih.gov/pubmed/24752170
http://dx.doi.org/10.1371/journal.pone.0094832