Characterization of a Novel Single-Chain Bispecific Antibody for Retargeting of T Cells to Tumor Cells via the TCR Co-Receptor CD8

There is currently growing interest in retargeting of effector T cells to tumor cells via bispecific antibodies (bsAbs). Usually, bsAbs are directed on the one hand to the CD3 complex of T cells and on the other hand to a molecule expressed on the surface of the target cell. A bsAb-mediated cross-li...

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Detalles Bibliográficos
Autores principales: Michalk, Irene, Feldmann, Anja, Koristka, Stefanie, Arndt, Claudia, Cartellieri, Marc, Ehninger, Armin, Ehninger, Gerhard, Bachmann, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994066/
https://www.ncbi.nlm.nih.gov/pubmed/24751697
http://dx.doi.org/10.1371/journal.pone.0095517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994066/
https://www.ncbi.nlm.nih.gov/pubmed/24751697
http://dx.doi.org/10.1371/journal.pone.0095517

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