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Independent Adipogenic and Contractile Properties of Fibroblasts in Graves’ Orbitopathy: An In Vitro Model for the Evaluation of Treatments

Graves’ orbitopathy (GO) is a disfiguring and sometimes blinding disease, characterised by inflammation and swelling of orbital tissues, with fibrosis and adipogenesis being predominant features. Little is known about the disease aetiology and the molecular mechanisms driving the phenotypic changes...

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Detalles Bibliográficos
Autores principales: Li, He, Fitchett, Caroline, Kozdon, Katarzyna, Jayaram, Hari, Rose, Geoffrey E., Bailly, Maryse, Ezra, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994071/
https://www.ncbi.nlm.nih.gov/pubmed/24751986
http://dx.doi.org/10.1371/journal.pone.0095586