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Independent Adipogenic and Contractile Properties of Fibroblasts in Graves’ Orbitopathy: An In Vitro Model for the Evaluation of Treatments
Graves’ orbitopathy (GO) is a disfiguring and sometimes blinding disease, characterised by inflammation and swelling of orbital tissues, with fibrosis and adipogenesis being predominant features. Little is known about the disease aetiology and the molecular mechanisms driving the phenotypic changes...
Autores principales: | Li, He, Fitchett, Caroline, Kozdon, Katarzyna, Jayaram, Hari, Rose, Geoffrey E., Bailly, Maryse, Ezra, Daniel G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994071/ https://www.ncbi.nlm.nih.gov/pubmed/24751986 http://dx.doi.org/10.1371/journal.pone.0095586 |
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