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RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis

Down Syndrome (DS) patients develop characteristic Alzheimer's Disease (AD) neuropathology after their middle age. Prominent neuronal loss has been observed in the cortical regions of AD brains. However, the underlying mechanism leading to this neuronal loss in both DS and AD remains to be eluc...

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Detalles Bibliográficos
Autores principales: Sun, Xiulian, Wu, Yili, Herculano, Bruno, Song, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994074/
https://www.ncbi.nlm.nih.gov/pubmed/24751678
http://dx.doi.org/10.1371/journal.pone.0095471