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RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis
Down Syndrome (DS) patients develop characteristic Alzheimer's Disease (AD) neuropathology after their middle age. Prominent neuronal loss has been observed in the cortical regions of AD brains. However, the underlying mechanism leading to this neuronal loss in both DS and AD remains to be eluc...
Autores principales: | Sun, Xiulian, Wu, Yili, Herculano, Bruno, Song, Weihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994074/ https://www.ncbi.nlm.nih.gov/pubmed/24751678 http://dx.doi.org/10.1371/journal.pone.0095471 |
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