Cargando…
The Role of the Niemann-Pick Disease, Type C1 Protein in Adipocyte Insulin Action
The Niemann-Pick disease, type C1 (NPC1) gene encodes a transmembrane protein involved in cholesterol efflux from the lysosome. SNPs within NPC1 have been associated with obesity and type 2 diabetes, and mice heterozygous or null for NPC1 are insulin resistant. However, the molecular mechanism under...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994084/ https://www.ncbi.nlm.nih.gov/pubmed/24752197 http://dx.doi.org/10.1371/journal.pone.0095598 |