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Synthesis and Mechanistic Studies of a Novel Homoisoflavanone Inhibitor of Endothelial Cell Growth

Preventing pathological ocular angiogenesis is key to treating retinopathy of prematurity, diabetic retinopathy and age-related macular degeneration. At present there is no small molecule drug on the market to target this process and hence there is a pressing need for developing novel small molecule...

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Detalles Bibliográficos
Autores principales: Basavarajappa, Halesha D., Lee, Bit, Fei, Xiang, Lim, Daesung, Callaghan, Breedge, Mund, Julie A., Case, Jamie, Rajashekhar, Gangaraju, Seo, Seung-Yong, Corson, Timothy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994091/
https://www.ncbi.nlm.nih.gov/pubmed/24752613
http://dx.doi.org/10.1371/journal.pone.0095694