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Synthesis and Mechanistic Studies of a Novel Homoisoflavanone Inhibitor of Endothelial Cell Growth
Preventing pathological ocular angiogenesis is key to treating retinopathy of prematurity, diabetic retinopathy and age-related macular degeneration. At present there is no small molecule drug on the market to target this process and hence there is a pressing need for developing novel small molecule...
Autores principales: | Basavarajappa, Halesha D., Lee, Bit, Fei, Xiang, Lim, Daesung, Callaghan, Breedge, Mund, Julie A., Case, Jamie, Rajashekhar, Gangaraju, Seo, Seung-Yong, Corson, Timothy W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994091/ https://www.ncbi.nlm.nih.gov/pubmed/24752613 http://dx.doi.org/10.1371/journal.pone.0095694 |
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