TAT-Protein Blockade during Ischemia/Reperfusion Reveals Critical Role for p85 PI3K-PTEN Interaction in Cardiomyocyte Injury

Recent work shows that cooling protection after mouse cardiac arrest and cardiomyocyte ischemia is mediated by Akt activation. The PI3K p85 subunit can either augment or inhibit Akt activation depending on its binding to p110 or PTEN respectively. To further clarify the role of PI3K p85 in cardiopro...

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Detalles Bibliográficos
Autores principales: Zhu, Xiangdong, Shao, Zuo-Hui, Li, Changqing, Li, Jing, Zhong, Qiang, Learoyd, Jonathan, Meliton, Angelo, Meliton, Lucille, Leff, Alan R., Vanden Hoek, Terry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994094/
https://www.ncbi.nlm.nih.gov/pubmed/24752319
http://dx.doi.org/10.1371/journal.pone.0095622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994094/
https://www.ncbi.nlm.nih.gov/pubmed/24752319
http://dx.doi.org/10.1371/journal.pone.0095622

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