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Developmental Changes of ENaC Expression and Function in the Inner Ear of Pendrin Knock-Out Mice as a Perspective on the Development of Endolymphatic Hydrops

Pendrin mutations cause enlarged vestibular aqueducts and various degrees of sensorineural hearing loss. The selective abolition of pendrin causes dilation of the membranous labyrinth known as endolymphatic hydrops, loss of the endocochlear potential, and consequently loss of hearing function. Becau...

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Detalles Bibliográficos
Autores principales: Kim, Bo Gyung, Kim, Jin Young, Kim, Hee Nam, Bok, Jinwoong, Namkung, Wan, Choi, Jae Young, Kim, Sung Huhn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994121/
https://www.ncbi.nlm.nih.gov/pubmed/24752462
http://dx.doi.org/10.1371/journal.pone.0095730