LAMTOR2-Mediated Modulation of NGF/MAPK Activation Kinetics during Differentiation of PC12 Cells

LAMTOR2 (p14), a part of the larger LAMTOR/Ragulator complex, plays a crucial role in EGF-dependent activation of p42/44 mitogen-activated protein kinases (MAPK, ERK1/2). In this study, we investigated the role of LAMTOR2 in nerve growth factor (NGF)-mediated neuronal differentiation. Stimulation of...

Descripción completa

Detalles Bibliográficos
Autores principales: Thauerer, Bettina, Voegele, Paul, Hermann-Kleiter, Natascha, Thuille, Nikolaus, de Araujo, Mariana E. G., Offterdinger, Martin, Baier, Gottfried, Huber, Lukas A., Baier-Bitterlich, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994133/
https://www.ncbi.nlm.nih.gov/pubmed/24752675
http://dx.doi.org/10.1371/journal.pone.0095863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994133/
https://www.ncbi.nlm.nih.gov/pubmed/24752675
http://dx.doi.org/10.1371/journal.pone.0095863

Ejemplares similares