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LAMTOR2-Mediated Modulation of NGF/MAPK Activation Kinetics during Differentiation of PC12 Cells

LAMTOR2 (p14), a part of the larger LAMTOR/Ragulator complex, plays a crucial role in EGF-dependent activation of p42/44 mitogen-activated protein kinases (MAPK, ERK1/2). In this study, we investigated the role of LAMTOR2 in nerve growth factor (NGF)-mediated neuronal differentiation. Stimulation of...

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Detalles Bibliográficos
Autores principales:	Thauerer, Bettina, Voegele, Paul, Hermann-Kleiter, Natascha, Thuille, Nikolaus, de Araujo, Mariana E. G., Offterdinger, Martin, Baier, Gottfried, Huber, Lukas A., Baier-Bitterlich, Gabriele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994133/ https://www.ncbi.nlm.nih.gov/pubmed/24752675 http://dx.doi.org/10.1371/journal.pone.0095863

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