Cargando…

Granulopoiesis Requires Increased C/EBPα Compared to Monopoiesis, Correlated with Elevated Cebpa in Immature G-CSF Receptor versus M-CSF Receptor Expressing Cells

C/EBPα is required for the formation of granulocyte-monocyte progenitors; however, its role in subsequent myeloid lineage specification remains uncertain. Transduction of murine marrow with either of two Cebpa shRNAs markedly increases monocyte and reduces granulocyte colonies in methylcellulose or...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Ou, Hong, SunHwa, Guo, Hong, Ghiaur, Gabriel, Friedman, Alan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994156/
https://www.ncbi.nlm.nih.gov/pubmed/24752325
http://dx.doi.org/10.1371/journal.pone.0095784