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Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis

BACKGROUND: There is conflicting evidence about the importance of airway mucins (MUC5AC and MUC5B) in determining physical properties of sputum in cystic fibrosis (CF). We studied the effects of endogenous degradation of mucins on CF sputum elasticity and apparent mucin concentrations. METHODS: Elas...

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Detalles Bibliográficos
Autores principales: Horsley, Alex, Rousseau, Karine, Ridley, Caroline, Flight, William, Jones, Andrew, Waigh, Thomas A., Thornton, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994278/
https://www.ncbi.nlm.nih.gov/pubmed/24332705
http://dx.doi.org/10.1016/j.jcf.2013.11.002